徐晓艳 副研究员

研究内容

长期从事博尔纳病病毒导致神经精神疾病发生发展的研究工作。主持和参与重庆市技术创新与应用发展项目1项，重庆市自然科学基金博士后项目2项（已结题1项）。作为主要完成人，研究相关成果获得贵州省科技进步二等奖（2019年），重庆市科技进步一等奖（2020年）。

代表性论文

1. Xu X, Guo Y, Tang T, Sun L, Zhang X, Shen X, Li D, Wang L, Zhao L, Xie P. miR-505 inhibits replication of Borna disease virus 1 via inhibition of HMGB1-mediated autophagy, Journal of General Virology, 2022, 103(1).

2. Xu X, Tang T, Guo Y, Zhao L, Shen X, Sun L, Xie P. BoDV-1 infection induces neuroinflammation by activating the TLR/ MyD88/IRF5 signaling pathway, leading to learning and memory impairment in rats, J Med Virol, 2021, 93(11)

3. Xu X, Jie J, Xia J, Tu Z, Guo Y, Li C, Zhang X, Wang H, Song W, Xie P. Memory Impairment Induced by Borna Disease Virus 1 Infection is Associated with Reduced H3K9 Acetylation, Cell Physiol Biochem, 2018, 49(1): 381- 394.

4. Xu X, Li C, Zhang X, Cheng K, Guo Y, Jie J, Guo H, He Y, Zhou C, Gui S, Zhong X, Wang H, Xie P. Activation of ERK/CREB/BDNF pathway involved in abnormal behavior of neonatally Borna virus-infected rats, Neuropsychiatr Dis Treat, 2018, 14: 3121-3132.